ALPHA-LACTALBUMIN ISOLATED FROM CAMEL MILK ON HYPERLIPIDEMIA AND HYPERGLYCEMIA IN EXPERIMENTAL MICE
DOI:
https://doi.org/10.31413/nat.v11i4.16333Palabras clave:
Camel milk, a-lactalbumin, Purification, hyperglycemia, hyperlipidemiaResumen
Este estudio investigó el efecto de la α-lactoalbúmina aislada de la leche de camello (a-Lac) en 200 y 400 mcg/día contra los trastornos metabólicos, la hiperlipidemia y la hiperglucemia en la lipidemia inducida por colesterol en ratones. Monitoree los signos vitales como el peso corporal, se observó el nivel de glucosa en sangre en ayunas cada semana hasta la semana 8 (la primera adaptación de 4 semanas y la segunda anormalidad, 4 semanas durante el tratamiento investigado), el nivel de la prueba de tolerancia oral a la glucosa (OGTT) y los parámetros bioquímicos se midieron después. las segundas 4 semanas en muestras de sangre y suero, como perfiles de lípidos, resistencia a la insulina y enzimas hepáticas, incluidas ALT, AST y ALP. Los resultados mostraron que el α-La de camello contribuyó eficazmente a mantener los indicadores vitales dentro de límites saludables y provocó disminuciones en el nivel de hiperlipidemia e hiperglucemia. Dio actividad a las enzimas hepáticas. Los resultados fueron con una clara diferencia estadística, recomendando el uso de proteínas de suero de camello y α-La en particular debido a su abundancia en la leche de camello y sus propiedades terapéuticas.
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